Human Hair Follicle Dermal Papilla Cells: HFDPC 人毛囊真皮乳頭細胞：HFDPC
產品型號： 602K-05a
Human Hair Follicle Dermal Papilla Cells (HFDPC) are mesenchymal cells isolated from the hair papilla of normal human scalp hair follicles. Hair papilla, in the adult hair follicle, plays a crucial role in the dermal-epidermal interactions that control hair production and events of the hair growth cycle. HFDPC can therefore be used for studying cellular mechanisms organizing the hair follicle, and for the development and evaluation of hair growth products.
HFDPC from Cell Applications, Inc. have been used to:
- Demonstrate that IL-1α affects dermal papilla activity by decreasing androgen receptor expression and stimulating secretion of KFG, VEGF, IL-8 and GM-CSF
- Investigate how gene expression and cell proliferation are affected by testosterone analogues, potential hair growth enhancing agents and microbial metabolites
- Study mechanisms of cellular senescence, and developed methodology to extend cellular life span and immortalize the cells by inhibiting p16INK4a and introducing hTERT
- Discover the link between the androgen-induced alopecia and circadian rhythms, mediated by a “clock gene” transcription factor BMAL1
DETAILS
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Tissue
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Normal human scalp hair follicle papilla
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QC
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No bacteria, yeast, fungi, mycoplasma, virus
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Bioassay
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Attach, spread, proliferate in Growth Med
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Cryovial
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500,000 HFDPC (2nd passage) in frozen in Basal Medium w/20% FBS & 5% DMSO
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Kit
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Frzn HFDPC (602-05a), Gr Med (611-500), Subcltr Rgnt Kit (090K), Coll Coated T-75 Flask (125-75), Coll Soln (125-50)
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Proliferating
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Shipped in Gr Med, 3rd psg (flasks or plates)
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Doublings
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At least 6
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Applications
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Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
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PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Cryopreserved HFDPC, Adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) | 1 Kit | 602K-05a |
| Cryopreserved HFDPC, Adult: Frozen HFDPC (5x10^5) | 1 Cryovial | 602-05a |
| Cryopreserved HFDPC, Top of Scalp, Adult: 5x10^5 Cells (Top of Scalp, Adult), Medium & Subculture Reagents (See Details tab for specifics) | 1 Kit | 602tK-05a |
| Cryopreserved HFDPC, Top of Scalp, Adult: Frozen HFDPC from Top of Scalp (5x10^5) | 1 Cryovial | 602t-05a |
| Proliferating HFDPC, Adult: Actively growing, dividing cells, in medium | T-25 Flask | 603-25a |
| Proliferating HFDPC, Adult: Actively growing, dividing cells, in medium | T-75 Flask | 603-75a |
RELATED PRODUCTS
| PRODUCT | SIZE | CAT.# |
| HFDPC Growth Medium: All-in-one ready-to-use | 500 ml | 611-500 |
| HFDPC Growth Medium Kit: Basal medium & growth supplement sold together packaged separately | Yields 500 ml | 611K-500 |
| HFDPC Basal Medium: Basal medium (contains no growth supplement). Add GS before use. | 500 ml | 610-500 |
| HFDPC Growth Supplement: Added to Basal Medium to create Growth Medium | 30 ml | 611-GS |
| Bovine Collagen Coating Solution: Bovine Collagen | 50 ml | 125-50 |
| Bovine Collagen Coating Solution: Bovine Collagen | 100 ml | 125-100 |
EXTENDED FAMILY PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Cyto-X Cell Counting Reagent Sample: 100 tests | Sample | 028-S |
| Cyto-X Cell Counting Reagent: 500 tests | 1 Bottle | 028-01 |
| HFDPC RNA, Adult: Total RNA prepared from Hair Follicle Dermal Papilla Cells, adult | 10 ug | 602-R10a |
| HFDPC RNA, Adult: Total RNA prepared from Hair Follicle Dermal Papilla Cells, adult | 25 ug | 602-R25a |
| Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | 1 Kit | 090K |
| HFDPC Growth Medium wo FBS: Growth medium without FBS | 500 ml | 611F-500 |
| HFDPC Growth Medium w/ 2% FBS: Growth medium with 2% FBS | 500 ml | 611F2-500 |
| HFDPC Growth Medium wo FBS or Cyproterone: Growth medium without FBS and cyproterone | 500 ml | 611FC-500 |
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