Human Mammary Epithelial Cells: HMEpC 人乳腺上皮細胞
產品型號： 830K-05A_830-05a
HMEpC from Cell Applications, Inc. have been utilized in numerous research publications, for example to:
- Investigate the role of exosomes secreted by cancer cells in formation of tumor permissive microenvironment through manipulation of normal mammary epithelium
- Serve as control in a study investigating antitumor properties of cannabinoids and stem cell microenvironment
- Determine that differential expression of glycoproteins allows classification of human breast cells into normal, benign, malignant, basal, and luminal groups
- Identify ALDH isoform 5A1 as a potential target for treatment of human breast ductal carcinoma
- Determine that combination of an anti-growth factor treatment using phototherapy (UV-B) is more effective
- Investigate cell survival following DNA damage
- Show the important roles of tumor suppressors in mammary epithelial differentiation
- Explain protection of extracellular matrix from degradation in normal mammary epithelia,
- Show that Maspin loss in metastatic cancer leads to unrestricted ECM degradation, contributing to metastasis, and that loss of EcSOD expression also promotes invasiveness by disrupting ECM
- Investigate the role of shortened telomeres in initiation of genomic instability, cytokinesis failure and polyploidy
- Elucidate the role of Myc in malignancy by studying its ability to transform primary epithelial cells
- Demonstrate, along with Human dermal Fibroblasts, also from Cell Applications, Inc., that resveratrol inhibits mono-ubiquitination of histone H2B
DETAILS
| Tissue | Normal healthy human mammary glands |
| QC | No bacteria, yeast, fungi, mycoplasma, virus |
| Bioassay | Attach, spread, proliferate in Growth med |
| Cryovial | 500,000 HMEpC (5th passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO |
| Kit | Cryovial frozen HMEpC(830-05a), Growth Med (815-500), Subculture Rgnt Kit (090K) |
| Proliferating | Shipped in Gr Med, 6th psg (flasks or plates) |
| Doublings | At least 16 |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Cryopreserved HMEpC, Adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) | 1 Kit | 830K-05a |
| Cryopreserved HMEpC, Adult: Frozen HMEpC (5x10^5) | 1 Cryovial | 830-05a |
| Proliferating HMEpC, Adult: Actively growing, dividing cells in medium | T-25 Flask | 831-25a |
| Proliferating HMEpC, Adult: Actively growing, dividing cells in medium | T-75 Flask | 831-75a |
RELATED PRODUCTS
| PRODUCT | SIZE | CAT.# |
| HMEpC Growth Medium: All-in-one ready-to-use | 500 ml | 815-500 |
| HMEpC Growth Medium Kit: Basal medium & growth supplement sold together packaged separately | Yields 500 ml | 815K-500 |
| HMEpC Basal Medium: Basal medium (contains no growth supplement). Add GS before use. | 500 ml | 814-500 |
| HMEpC Growth Supplement: Added to Basal Medium to create Growth Medium | 5 ml | 815-GS |
EXTENDED FAMILY PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | 1 Kit | 090K |
| HMEpC RNA, Adult: Total RNA prepared from Human Mammary Epithelial Cells, adult | 10 ug | 830-R10a |
| HMEpC RNA, Adult: Total RNA prepared from Human Mammary Epithelial Cells, adult | 25 ug | 830-R25a |
| Monoclonal IL-1 Receptor Antagonist Antibody: Monoclonal IL-1 Receptor Antagonist Antibody | 100 ul | CB19846 |
| Freezing Medium: For general cryopreservation of most primary cells. Contains FBS & DMSO. | 50 ml | 040-50 |
| Cytofect™ Epithelial Cell Transfection Kit: 124 x 24-Well Rxns | 1 Kit | TF102K |
| Cytofect™ Epithelial Cell Transfection Kit: 25 x 24-Well Rxns | 1 Sample Kit | TF102KS |
| Cyto-X Cell Counting Reagent: 500 tests | 1 Bottle | 028-01 |
| Cyto-X Cell Counting Reagent Sample: 100 tests | Sample | 028-S |
| Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor | 100 ug | RP1026-100 |
| Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor | 500 ug | RP1026-500 |
| Human Epidermal Growth Factor (EGF): Human Epidermal Growth Factor | 1000 ug | RP1026-1000 |
| Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha | 10 ug | RP1173-10 |
| Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha | 100 ug | RP1173-100 |
| Human Interleukin-1-Alpha (IL-1 alpha): Human Interleukin-1-alpha | 1000 ug | RP1173-1000 |
| Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free | 100 ug | RP1026AF-100 |
| Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free | 500 ug | RP1026AF-500 |
| Human EGF, Animal-Free: Human Epidermal Growth Factor, Animal-Free | 1000 ug | RP1026AF-1000 |
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