Canine Osteoblasts: CnOb 犬成骨細胞：CnOb
產品型號： Cn406K-05
Canine Osteoblasts (CnOb) from Cell Applications, Inc. provide an excellent model system for studies relevant to the skeletal system, including mechanisms of cancerogenesis.
Our CnOb. have been used to:
- Define a biomarker profile of canine osteosarcoma, elucidate the roles of oncogenic STAT3 and canonical Wnt signaling pathways
- Develop personalized osteosarcoma treatments by testing Src inhibitor dasatinib, procaspase-3 activating compound PAC-1, HSP90 inhibitor STA‐1474 and STAT3 inhibitor LLL12.
Characterization: Positive for bone mineralization
DETAILS
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Tissue
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Normal healthy canine bone.
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QC
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No bacteria, yeast, fungi, mycoplasma
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Character
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Bone mineralization (von Kossa stain)
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Bioassay
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Attach, spread, proliferate in Growth Med
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Cryovial
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500,000 CnOb (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO
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Kit
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Cryovial frozen CnOb (Cn406-05), Growth Med (Cn417-500), Subcltr Rgnt Kit (090K)
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Proliferating
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Shipped in Gr Med, 2nd psg (flasks or plates)
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Doublings
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At least 10
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Applications
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Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
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PRODUCTS
| PRODUCT | SIZE | CAT.# |
| Cryopreserved CnOb: 5x10^5 Cells, Medium & Subculture Reagents (See Details tab for specifics) | 1 Kit | Cn406K-05 |
| Cryopreserved CnOb: Frozen CnOb (5x10^5) | 1 Cryovial | Cn406-05 |
| Proliferating CnOb: Actively growing, dividing cells in medium | T-25 Flask | Cn407-25 |
| Proliferating CnOb: Actively growing, dividing cells in medium | T-75 Flask | Cn407-75 |
RELATED PRODUCTS
| PRODUCT | SIZE | CAT.# |
| CnOb Basal Medium: Basal medium (contains no growth supplement). Add GS before use. | 500 ml | Cn416-500 |
| CnOb Growth Medium: All-in-one ready-to-use | 500 ml | Cn417-500 |
| CnOb Growth Medium Kit: Basal medium & growth supplement sold together packaged separately | Yields 500ml | Cn417K-500 |
| CnOb Differentiation Medium: Promotes cells to change from one type to another, more specialized | 250 ml | Cn417D-250 |
| CnOb Growth Supplement: Added to Basal Medium to create Growth Medium | 30 ml | Cn417-GS |
EXTENDED FAMILY PRODUCTS
| Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | 1 Kit | 090K |
| PRODUCT | SIZE | CAT.# |
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